PrimeX Testo Max The above review also leaves out other known effects of low T, such as loss of libido, depression, loss of muscle mass and decreases performance, as well as other issues best avoided. Most studies find clear PrimeX Testo Max health benefits for men with hypogonadism treated with HRT. However, some fears of long term side effects such as cardio vascular disease (CVD) and prostate cancer have been raised. These fears appear to be unfounded, with benefits to the cardio vascular system for men low in T.